ID   WGA
AC   CVCL_0578
DR   MCCL; MCC:0000484
DR   Wikidata; Q54993989
RX   PubMed=15572372;
CC   Population: Caucasian.
CC   Characteristics: Derived from the parent cell line by metabolic selection using the ability to grow on fructose as the selection system.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 20-05-21; Version: 14
//
RX   PubMed=15572372; DOI=10.1074/jbc.M412711200;
RA   Rencurel F., Stenhouse A., Hawley S.A., Friedberg T., Hardie D.G.,
RA   Sutherland C., Wolf C.R.;
RT   "AMP-activated protein kinase mediates phenobarbital induction of
RT   CYP2B gene expression in hepatocytes and a newly derived human
RT   hepatoma cell line.";
RL   J. Biol. Chem. 280:4367-4373(2005).
//