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Cellosaurus Kasumi-6 (CVCL_0614)

[Text version]

Cell line name Kasumi-6
Synonyms KASUMI-6; KASUMI6
Accession CVCL_0614
Resource Identification Initiative To cite this cell line use: Kasumi-6 (RRID:CVCL_0614)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~70 hours (DSMZ).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for CEBPA p.Arg306Pro (c.917G>C) (PubMed=12508245; CCLE).
Homozygous for TP53 p.Tyr234Asp (c.700T>G) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.79
Native American0
East Asian, North75.55
East Asian, South23.65
South Asian0
European, North0
European, South0
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): ATCC; DSMZ; JCRB

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811
D7S8209,11
D13S3178,12
D16S5399,10
TH016,9
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=12508245; DOI=10.1002/gcc.10161
Asou H., Gombart A.F., Takeuchi S., Tanaka H., Tanioka M., Matsui H., Kimura A., Inaba T., Koeffler H.P.
Establishment of the acute myeloid leukemia cell line Kasumi-6 from a patient with a dominant-negative mutation in the DNA-binding region of the C/EBPalpha gene.
Genes Chromosomes Cancer 36:167-174(2003)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940-940(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections ATCC; CRL-2775
DSMZ; ACC-686
JCRB; JCRB1024
JCRB; NIHS0314 - Discontinued
Cell line databases/resources CCLE; KASUMI6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
DepMap; ACH-000166
Ontologies CLO; CLO_0007072
Biological sample resources BioSample; SAMN03471785
BioSample; SAMN10988477
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887199
GEO; GSM888272
GEO; GSM1374592
Other Wikidata; Q54899523
Polymorphism and mutation databases IARC_TP53; 28325
LiGeA; CCLE_218
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number18