Cellosaurus SK-LMS-1 (CVCL_0628)

Cell line name SK-LMS-1
Synonyms SKLMS-1; SKLMS1
Accession CVCL_0628
Resource Identification Initiative To cite this cell line use: SK-LMS-1 (RRID:CVCL_0628)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: MD Anderson Cell Lines Project.
From: Memorial Sloan-Kettering Cancer Center; New York; USA.
Microsatellite instability: Stable (MSS) (Sanger).
Sequence variation: TP53 p.Met237Lys and p.Gly245Ser (PubMed=16142349).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Vulvar leiomyosarcoma (NCIt: C40318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_8591 (SK-Ala-1); CVCL_8592 (SK-Ala-10); CVCL_8593 (SK-Ala-14); CVCL_8594 (SK-Ala-2); CVCL_8595 (SK-Ala-21); CVCL_8596 (SK-Ala-3); CVCL_8597 (SK-Neo); CVCL_8598 (SK-p53-1); CVCL_8599 (SK-p53-2); CVCL_8600 (SK-p53-3)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; CLS; Cosmic-CLP

Markers:
AmelogeninX
CSF1PO9,10
D13S31712 (ATCC; CLS)
11,12 (Cosmic-CLP)
D16S5398,11
D18S5114,19
D21S1128,30
D3S135815,16
D5S81811,13
D7S8208,9
D8S117912
FGA22,25
Penta D12,13
Penta E7,13
TH016,7
TPOX8,9
vWA18,20 (ATCC; Cosmic-CLP)
18 (CLS)
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/s/cell-lines-detail-476.html
http://tcpaportal.org/mclp/
Publications

DOI=10.1007/978-1-4757-1647-4_5
Fogh J., Trempe G.L.
New human tumor cell lines.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.115-159; Springer; New York (1975)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=7459858
Rousset M., Zweibaum A., Fogh J.
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)

PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=16142349; DOI=10.3892/or.14.4.901
Smardova J., Pavlova S., Svitakova M., Grochova D., Ravcukova B.
Analysis of p53 status in human cell lines using a functional assay in yeast: detection of new non-sense p53 mutation in codon 124.
Oncol. Rep. 14:901-907(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074
Teicher B.A., Polley E., Kunkel M., Evans D., Silvers T.E., Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J., Harris E., Monks A., Morris J.
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections ATCC; HTB-88
CLS; 300125/p629_SK-LMS-1
Cell line databases/resources CCLE; SKLMS1_SOFT_TISSUE
Cosmic-CLP; 909720
GDSC; 909720
IGRhCellID; SKLMS1
LINCS_HMS; 50042
LINCS_LDP; LCL-1286
Ontologies BTO; BTO:0002607
CLO; CLO_0009038
EFO; EFO_0002331
Biological sample resources BioSample; SAMN03472759
Chemistry resources ChEMBL-Cells; CHEMBL3308552
ChEMBL-Targets; CHEMBL2366096
Gene expression databases GEO; GSM887579
GEO; GSM888662
GEO; GSM1670433
GEO; GSM1676326
GEO; GSM1701659
Polymorphism and mutation databases Cosmic; 687594
Cosmic; 909720
Cosmic; 1834891