Cell line name | SK-MES-1 | ||||||||||||||||||||||||||||||||||||
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Synonyms | SK MES 1; SKMES-1; SK-Mes-1; SK-MES1; SKMES1; SK-MES; SKMES | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0630 | ||||||||||||||||||||||||||||||||||||
Secondary accession | CVCL_8913 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: SK-MES-1 (RRID:CVCL_0630) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: MD Anderson Cell Lines Project. From: Memorial Sloan Kettering Cancer Center; New York; USA. Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2009-091. Doubling time: ~50 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||||||||||||||||||||
Sequence variations | Homozygous for TP53 p.Glu298Ter (c.892G>T) (ClinVar=VCV000093323) (PubMed=12794755; CCLE; Cosmic-CLP). | ||||||||||||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Lung squamous cell carcinoma (NCIt: C3493) Derived from metastatic site: Pleural effusion. | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 65Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): AddexBio; ATCC; CLS; Cosmic-CLP; DSMZ; KCLB; PubMed=25877200 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-mes-1-lung-cell-line http://tcpaportal.org/mclp/ http://www.cellresource.cn/fdetail.aspx?id=262 http://www.cellresource.cn/fdetail.aspx?id=678 http://www.cellresource.cn/fdetail.aspx?id=2183 | ||||||||||||||||||||||||||||||||||||
Publications | DOI=10.1007/978-1-4757-1647-4_5 PubMed=833871; DOI=10.1093/jnci/58.2.209 PubMed=6935474; DOI=10.1093/jnci/66.2.239 PubMed=7017212; DOI=10.1093/jnci/66.6.1003 PubMed=2990217 PubMed=4005855 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=3335022 PubMed=8385084; DOI=10.1111/j.1349-7006.1993.tb02851.x PubMed=7736387; DOI=10.1002/1097-0142(19950515)75:10<2442::AID-CNCR2820751009>3.0.CO;2-Q PubMed=11583962; DOI=10.1016/S0002-9440(10)62521-7 PubMed=12794755; DOI=10.1002/ijc.11184 PubMed=14581340 PubMed=15746151; DOI=10.1093/hmg/ddi092 PubMed=18083107; DOI=10.1016/j.cell.2007.11.025 PubMed=19472407; DOI=10.1002/humu.21028 PubMed=20164919; DOI=10.1038/nature08768 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22460905; DOI=10.1038/nature11003 PubMed=24002593; DOI=10.1038/bjc.2013.452 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections | AddexBio; C0016029/4989
ATCC; HTB-58 CLS; 300339/p1465_SK-MES-1 DSMZ; ACC-353 ECACC; 91091804 - Discontinued ECACC; 93120837 ICLC; HTL95004 IZSLER; BS TCL 72 KCB; KCB 200821YJ KCLB; 30058 NCBI_Iran; C562 NCI-DTP; SK-MES-1 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLDB; cl4325
CLDB; cl4326 CLDB; cl4329 CCLE; SKMES1_LUNG CCRID; 3111C0001CCC000262 CCRID; 3131C0001000700110 CCRID; 3142C0001000000946 Cell_Model_Passport; SIDM01103 CGH-DB; 191-1 CGH-DB; 9180-4 Cosmic-CLP; 909728 DepMap; ACH-000665 IGRhCellID; SKMES1 LINCS_HMS; 50043 LINCS_LDP; LCL-1583 TOKU-E; 3142 | ||||||||||||||||||||||||||||||||||||
Ontologies | BTO; BTO:0002203
CLO; CLO_0009033 CLO; CLO_0009048 CLO; CLO_0009049 EFO; EFO_0002334 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03473164
BioSample; SAMN10987781 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307450
ChEMBL-Targets; CHEMBL614923 GDSC; 909728 PharmacoDB; SKMES1_1401_2019 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM62971 GEO; GSM206544 GEO; GSM274789 GEO; GSM274819 GEO; GSM513971 GEO; GSM514561 GEO; GSM784266 GEO; GSM827318 GEO; GSM887590 GEO; GSM888673 GEO; GSM1374881 GEO; GSM1670444 | ||||||||||||||||||||||||||||||||||||
Other | Wikidata; Q54954357 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687832
Cosmic; 909728 Cosmic; 933577 Cosmic; 934464 Cosmic; 1006538 Cosmic; 1071896 Cosmic; 1089225 Cosmic; 1176620 Cosmic; 1219089 Cosmic; 1239912 Cosmic; 1434962 Cosmic; 1995637 Cosmic; 2060529 Cosmic; 2125289 Cosmic; 2696402 Cosmic; 2772162 IARC_TP53; 8201 IARC_TP53; 18793 LiGeA; CCLE_382 Progenetix; CVCL_0630 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||||||||||||||||||||
Version number | 32 |