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Cellosaurus Hs 445 (CVCL_0761)

Cell line name Hs 445
Synonyms HS-445; Hs-445; HS 445T; Hs445
Accession CVCL_0761
Resource Identification Initiative To cite this cell line use: Hs 445 (RRID:CVCL_0761)
Comments Problematic cell line: Misidentified. Originally thought to be a Hodgkin's cell line but is a B-lymphoblastoid cell line (PubMed=12592342).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 56Y
Category Transformed cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX
CSF1PO10.3,11 (ATCC)
11 (Cosmic-CLP)
D13S31711,13
D16S5399,11 (ATCC)
9 (Cosmic-CLP)
D5S8189,12
D7S8209,10
TH016,7
TPOX8
vWA14,17
Publications

PubMed=6500159; DOI=10.1159/000163283
Gershwin M.E., Lentz D., Owens R.B.
Relationship between karyotype of tissue culture lines and tumorigenicity in nude mice.
Exp. Cell Biol. 52:361-370(1984)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; HTB-146
Cell line databases/resources CCLE; HS445_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 1322218
GDSC; 1322218
LINCS_LDP; LCL-2006
Ontologies CLO; CLO_0003962
Biological sample resources BioSample; SAMN03472720
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669894
Other Wikidata; Q54895678