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Cellosaurus Hs 578Bst (CVCL_0807)

[Text version]

Cell line name Hs 578Bst
Synonyms Hs578Bst; HS578BST; Hs-578Bst; Hs 578.Bst; Homo sapiens No. 578, breast cells
Accession CVCL_0807
Resource Identification Initiative To cite this cell line use: Hs 578Bst (RRID:CVCL_0807)
Comments Part of: ICBP43 breast cancer cell line panel.
Omics: Mitochondrial genome sequenced.
Caution: Although it is part of a cancer cell line panel, it is a normal fibroblastic epithelial/myoepithelial cell line.
Misspelling: Hs57Bst; In DOI=10.1016/B978-0-12-333530-2.50009-5.
Sequence variations Heteroplasmic for MT-CYB p.Ala125Thr (m.G15119A); less <1% while homoplasmic in autologous cell line Hs 578T (PubMed=29671673).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_S253 ! Hs 578.Mg
CVCL_0332 ! Hs 578T
Sex of cell Female
Age at sampling 74Y
Category Finite cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO11,13
D5S81811,13
D7S82010
D13S31711,13
D16S5399,12
TH019,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Web pages http://lincs.hms.harvard.edu/resources/reagents/icbp43/
Publications

PubMed=864756; DOI=10.1093/jnci/58.6.1795
Hackett A.J., Smith H.S., Springer E.L., Owens R.B., Nelson-Rees W.A., Riggs J.L., Gardner M.B.
Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines.
J. Natl. Cancer Inst. 58:1795-1806(1977)

DOI=10.1016/B978-0-12-333530-2.50009-5
Leibovitz A.
Cell lines from human breast.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994)

PubMed=29671673; DOI=10.1080/24701394.2018.1461852
Hedberg A., Knutsen E., Lovhaugen A.S., Jorgensen T.E., Perander M., Johansen S.D.
Cancer-specific SNPs originate from low-level heteroplasmic variants in human mitochondrial genomes of a matched cell line pair.
Mitochondrial DNA A. DNA Mapp. Seq. Anal. 30:82-91(2019)

Cross-references
Cell line collections ATCC; HTB-125
IZSLER; BS CL 190
Cell line databases/resources CLDB; cl1715
CCRID; 3131C0001000200016
Ontologies BTO; BTO:0003886
CLO; CLO_0004008
Biological sample resources BioSample; SAMN03471102
Other Wikidata; Q54895773
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number18