ID   Hs 578Bst
AC   CVCL_0807
SY   Hs578Bst; HS578BST; Hs-578Bst; Hs 578.Bst; Homo sapiens No. 578, breast cells
DR   BTO; BTO:0003886
DR   CLO; CLO_0004008
DR   CLDB; cl1715
DR   ATCC; HTB-125
DR   BioSample; SAMN03471102
DR   CCRID; 3101HUMGNHu16
DR   IZSLER; BS CL 190
DR   PharmacoDB; HS578BST_617_2019
DR   Wikidata; Q54895773
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RX   PubMed=864756;
RX   PubMed=29671673;
WW   https://lincs.hms.harvard.edu/resources/reagents/icbp43/
CC   Part of: ICBP43 breast cancer cell line panel.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7427; MT-CYB; Simple; p.Ala125Thr (m.15119G>A); ClinVar=VCV000693829; Zygosity=Heteroplasmic; Note=Less <1% while homoplasmic in autologous cell line Hs 578T (PubMed=29671673).
CC   Omics: Mitochondrial genome sequenced.
CC   Caution: Although it is part of a cancer cell line panel, it is a normal fibroblastic epithelial/myoepithelial cell line.
CC   Misspelling: Hs57Bst; DOI=10.1016/B978-0-12-333530-2.50009-5.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 11,13
ST   D16S539: 9,12
ST   D5S818: 11,13
ST   D7S820: 10
ST   TH01: 9,9.3
ST   TPOX: 8
ST   vWA: 17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_S253 ! Hs 578.Mg
OI   CVCL_0332 ! Hs 578T
SX   Female
AG   74Y
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 25
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RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RA   Leibovitz A.;
RT   "Cell lines from human breast.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994).
//
RX   PubMed=864756; DOI=10.1093/jnci/58.6.1795;
RA   Hackett A.J., Smith H.S., Springer E.L., Owens R.B., Nelson-Rees W.A.,
RA   Riggs J.L., Gardner M.B.;
RT   "Two syngeneic cell lines from human breast tissue: the aneuploid
RT   mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst)
RT   cell lines.";
RL   J. Natl. Cancer Inst. 58:1795-1806(1977).
//
RX   PubMed=29671673; DOI=10.1080/24701394.2018.1461852;
RA   Hedberg A., Knutsen E., Lovhaugen A.S., Jorgensen T.E., Perander M.,
RA   Johansen S.D.;
RT   "Cancer-specific SNPs originate from low-level heteroplasmic variants
RT   in human mitochondrial genomes of a matched cell line pair.";
RL   Mitochondrial DNA A. DNA Mapp. Seq. Anal. 30:82-91(2019).
//