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Cellosaurus Hs 821.T (CVCL_0932)

[Text version]

Cell line name Hs 821.T
Synonyms Hs821T; HS821T
Accession CVCL_0932
Resource Identification Initiative To cite this cell line use: Hs 821.T (RRID:CVCL_0932)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.92
Native American46.51
East Asian, North5.29
East Asian, South0
South Asian1.88
European, North22.78
European, South21.62
Disease Malignancy in giant cell tumor of bone (NCIt: C4304)
Giant cell tumor of bone (ORDO: Orphanet_363976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0931 ! Hs 821.Sk
Sex of cell Female
Age at sampling 31Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO12,13
D5S81812,13
D7S82010,12
D13S3179,11
D16S53910,12
TH017,9.3
TPOX8,11
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections ATCC; CRL-7554
Cell line databases/resources CCLE; HS821T_FIBROBLAST
DepMap; ACH-000526
Ontologies CLO; CLO_0004139
Biological sample resources BioSample; SAMN10988537
Chemistry resources PharmacoDB; Hs821_T_598_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887119
GEO; GSM888190
Other Wikidata; Q54896087
Polymorphism and mutation databases IARC_TP53; 30064
LiGeA; CCLE_842
Progenetix; CVCL_0932
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number17