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Cellosaurus Capan1M9 (CVCL_0A59)

[Text version]

Cell line name Capan1M9
Accession CVCL_0A59
Resource Identification Initiative To cite this cell line use: Capan1M9 (RRID:CVCL_0A59)
Comments Characteristics: Highly migratory cell subclone of Capan-1.
Sequence variations Hemizygous for BRCA2 p.Ser1982Argfs*22 (c.5946delT) (6174delT) (ClinVar=VCV000009325) (from parent cell line).
Homozygous for FZD10 p.Asn54Lys (c.162C>A) (from parent cell line).
Heterozygous for GLT6D1 p.Trp198Ter (c.593G>A) (from parent cell line).
Homozygous for GRM1 p.Tyr486Ter (c.1458C>A) (from parent cell line).
Homozygous for KRAS p.Gly12Val (c.35G>T) (ClinVar=VCV000012583) (from parent cell line).
Homozygous for MAP2K4 p.Glu221Ter (c.661G>T) (from parent cell line).
Homozygous for SMAD4 p.Ser243Ter (c.1028C>G) (from parent cell line).
Heterozygous for SMAP2 p.Ser255Ter (c.764C>G) (from parent cell line).
TP53 p.Ala159Val (c.476C>T) (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0237 (Capan-1)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=22109279; DOI=10.1007/s13577-011-0037-9
Ding Q., Yoshimitsu M., Kuwahata T., Maeda K., Hayashi T., Obara T., Miyazaki Y., Matsubara S., Natsugoe S., Takao S.
Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer.
Hum. Cell 25:1-8(2012)

Cross-references
Other Wikidata; Q54808592
Entry history
Entry creation10-Apr-2015
Last entry update02-Jul-2020
Version number8