ID   Capan1M9
AC   CVCL_0A59
DR   cancercelllines; CVCL_0A59
DR   Wikidata; Q54808592
RX   PubMed=22109279;
CC   Population: Caucasian.
CC   Characteristics: Highly migratory cell subclone of Capan-1.
CC   Sequence variation: Mutation; HGNC; 1101; BRCA2; Simple; p.Ser1982Argfs*22 (c.5946delT) (6174delT); ClinVar=VCV000009325; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4039; FZD10; Simple; p.Asn54Lys (c.162C>A); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 23671; GLT6D1; Simple; p.Trp198Ter (c.593G>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4593; GRM1; Simple; p.Tyr486Ter (c.1458C>A); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6844; MAP2K4; Simple; p.Glu221Ter (c.661G>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6770; SMAD4; Simple; p.Ser343Ter (c.1028C>G); ClinVar=VCV000822036; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 25082; SMAP2; Simple; p.Ser255Ter (c.764C>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ala159Val (c.476C>T); ClinVar=VCV000458545; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0237 ! Capan-1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 05-10-23; Version: 15
//
RX   PubMed=22109279; DOI=10.1007/s13577-011-0037-9;
RA   Ding Q., Yoshimitsu M., Kuwahata T., Maeda K., Hayashi T., Obara T.,
RA   Miyazaki Y., Matsubara S., Natsugoe S., Takao S.;
RT   "Establishment of a highly migratory subclone reveals that CD133
RT   contributes to migration and invasion through epithelial-mesenchymal
RT   transition in pancreatic cancer.";
RL   Hum. Cell 25:1-8(2012).
//