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Cellosaurus OSCA-02 (CVCL_0A74)

[Text version]
Cell line name OSCA-02
Synonyms OSCA-2; OSCA2; OSA2
Accession CVCL_0A74
Resource Identification Initiative To cite this cell line use: OSCA-02 (RRID:CVCL_0A74)
Comments Omics: Genome sequenced.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Rottweiler.
Sex of cell Male
Age at sampling 9Y
Category Cancer cell line
STR profile Source(s): PubMed=36099278

Markers:
Dog FHC2010226,238
Dog FHC2054151,155
Dog FHC2079287
Dog PEZ1108,120
Dog PEZ12274,286
Dog PEZ20188
Dog PEZ3120
Dog PEZ5103
Dog PEZ6175,179
Dog PEZ8234,238

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Publications

PubMed=21621658; DOI=10.1016/j.bone.2011.05.008
Scott M.C., Sarver A.L., Gavin K.J., Thayanithy V., Getzy D.M., Newman R.A., Cutter G.R., Lindblad-Toh K., Kisseberth W.C., Hunter L.E., Subramanian S., Breen M., Modiano J.F.
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach.
Bone 49:356-367(2011)

PubMed=23365669; DOI=10.1371/journal.pone.0054464
Wells J.W., Evans C.H., Scott M.C., Rutgen B.C., O'Brien T.D., Modiano J.F., Cvetkovic G., Tepic S.
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
PLoS ONE 8:E54464-E54464(2013)

PubMed=36099278; DOI=10.1371/journal.pone.0274383
Megquier K., Turner-Maier J., Morrill K., Li X., Johnson J., Karlsson E.K., London C.A., Gardner H.L.
The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations.
PLoS ONE 17:E0274383-E0274383(2022)

Cross-references
Encyclopedic resources Wikidata; Q54936594
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number7