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Cellosaurus H69/VP (CVCL_0B23)

[Text version]

Cell line name H69/VP
Accession CVCL_0B23
Resource Identification Initiative To cite this cell line use: H69/VP (RRID:CVCL_0B23)
Comments Selected for resistance to: ChEBI; CHEBI:4911; Etoposide (VP-16).
Sequence variations Heterozygous for PIK3CA p.Gly106_Arg108del (c.317_325dellGGCAACCGT) (from parent cell line).
Homozygous for RB1 p.Glu748Ter (c.2242G>T) (from parent cell line).
Homozygous for TP53 p.Glu171Ter (c.511G>T) (ClinVar=VCV000634771) (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line

PubMed=8784480; DOI=10.1159/000227600
Shinohara A., Shimizu E., Takada M., Sone S.
Lack of c-mpl proto-oncogene transcripts and growth-stimulatory effects of thrombopoietin on human small cell lung cancer cell lines.
Oncology 53:426-434(1996)

PubMed=9062409; DOI=10.1038/bjc.1997.154
Jensen P.B., Holm B., Sorensen M., Christensen I.J., Sehested M.
In vitro cross-resistance and collateral sensitivity in seven resistant small-cell lung cancer cell lines: preclinical identification of suitable drug partners to taxotere, taxol, topotecan and gemcitabin.
Br. J. Cancer 75:869-877(1997)

Other Wikidata; Q54872203
Entry history
Entry creation10-Apr-2015
Last entry update02-Jul-2020
Version number8