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Cellosaurus Caki-dTub (CVCL_0B30)

[Text version]

Cell line name Caki-dTub
Accession CVCL_0B30
Resource Identification Initiative To cite this cell line use: Caki-dTub (RRID:CVCL_0B30)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:88246; 2'-deoxytubercidin.
Sequence variations Mutation; HGNC; 9884; RB1; Simple; p.Leu98Pro (c.293T>C); Zygosity=Heterozygous (from parent cell line).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Derived from metastatic site: Skin.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0234 (Caki-1)
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line

Pan B.F., Nelson J.A.
Multidrug resistance and collateral sensitivity in a human renal carcinoma selected for resistance to 2'-deoxytubercidin.
UroOncology 1:165-174(2001)

PubMed=17009030; DOI=10.1007/s00280-006-0351-1
Pan B.F., Nelson J.A.
Dihydrodiol dehydrogenase in drug resistance and sensitivity of human carcinomas.
Cancer Chemother. Pharmacol. 59:697-702(2007)

Ontologies BTO; BTO:0005559
Other Wikidata; Q54808380
Entry history
Entry creation10-Apr-2015
Last entry update20-May-2021
Version number9