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Cellosaurus RPK-59 (CVCL_0B32)

Cell line name RPK-59
Synonyms RPK59
Accession CVCL_0B32
Resource Identification Initiative To cite this cell line use: RPK-59 (RRID:CVCL_0B32)
Comments Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Omics: Transcriptome analysis.
Sequence variations KRAS p.Gly12Asp (c.35G>A) (PubMed=22490663).
Disease Pancreatic carcinoma (NCIt: C3850)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4897 (PK-59)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A.
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Ontologies BTO; BTO:0005471
Gene expression databases GEO; GSM862573
GEO; GSM862575
Other Wikidata; Q54951155