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Cellosaurus 228A (CVCL_0B43)

[Text version]
Cell line name 228A
Accession CVCL_0B43
Resource Identification Initiative To cite this cell line use: 228A (RRID:CVCL_0B43)
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly279Glu (c.836G>A); ClinVar=VCV000419454; Zygosity=Unspecified (PubMed=9620551).
Disease Embryonal carcinoma (NCIt: C3752)
Embryonal carcinoma (ORDO: Orphanet_180226)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=9620551; DOI=10.1038/sj.onc.1201770
Houldsworth J., Xiao H., Murty V.V.V.S., Chen W.-Y., Ray B., Reuter V.E., Bosl G.J., Chaganti R.S.K.
Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation.
Oncogene 16:2345-2349(1998)

PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868
Feldman D.R., Iyer G., Van Alstine L., Patil S., Al-Ahmadie H., Reuter V.E., Bosl G.J., Chaganti R.S.K., Solit D.B.
Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.
Clin. Cancer Res. 20:3712-3720(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0B43
Encyclopedic resources Wikidata; Q54583373
Polymorphism and mutation databases Cosmic; 2163761
Entry history
Entry creation10-Apr-2015
Last entry update05-Oct-2023
Version number9