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Cellosaurus 2A3 [Human squamous cell carcinoma] (CVCL_0D71)

[Text version]

Cell line name 2A3 [Human squamous cell carcinoma]
Accession CVCL_0D71
Resource Identification Initiative To cite this cell line use: 2A3 [Human squamous cell carcinoma] (RRID:CVCL_0D71)
Sequence variations Homozygous for CDKN2A c.151-1G>T; splice acceptor mutation (from parent cell line).
Heterozygous for TP53 p.Arg248Leu (c.743G>T) (ClinVar=VCV000230253) and c.376-1G>A (p.Tyr126_Lys132del; c.376_396del21); splice acceptor mutation (from parent cell line).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1218 (FaDu)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninNot_detected
CSF1PO12
D5S81812
D7S82011,12
D13S3178,9
D16S53911
TH018
TPOX11
vWA15,17

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Publications

PubMed=21314983; DOI=10.1186/1758-3284-3-9
Harris M., Wang X.G., Jiang Z., Goldberg G.L., Casadevall A., Dadachova E.
Radioimmunotherapy of experimental head and neck squamous cell carcinoma (HNSCC) with E6-specific antibody using a novel HPV-16 positive HNSCC cell line.
Head Neck Oncol. 3:9-9(2011)

Cross-references
Cell line collections ATCC; CRL-3212
Other Wikidata; Q54584291
Entry history
Entry creation10-Apr-2015
Last entry update02-Jul-2020
Version number8