ID   2A3 [Human squamous cell carcinoma]
AC   CVCL_0D71
DR   ATCC; CRL-3212
DR   cancercelllines; CVCL_0D71
DR   Wikidata; Q54584291
RX   PubMed=21314983;
CC   Population: Indian.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; c.151-1G>T; ClinVar=VCV000422058; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3595; FAT1; Simple; p.Lys3277Asnfs*4 (c.9828delG) (p.Gly3276fs); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Leu (c.743G>T); ClinVar=VCV000230253; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
ST   Source(s): ATCC
ST   Amelogenin: Not_detected
ST   CSF1PO: 12
ST   D13S317: 8,9
ST   D16S539: 11
ST   D5S818: 12
ST   D7S820: 11,12
ST   TH01: 8
ST   TPOX: 11
ST   vWA: 15,17
DI   NCIt; C4043; Hypopharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_494547; Squamous cell carcinoma of the hypopharynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1218 ! FaDu
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 05-10-23; Version: 15
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RX   PubMed=21314983; DOI=10.1186/1758-3284-3-9;
RA   Harris M., Wang X.-G., Jiang Z.-W., Goldberg G.L., Casadevall A.,
RA   Dadachova E.;
RT   "Radioimmunotherapy of experimental head and neck squamous cell
RT   carcinoma (HNSCC) with E6-specific antibody using a novel HPV-16
RT   positive HNSCC cell line.";
RL   Head Neck Oncol. 3:9.1-9.7(2011).
//