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Cellosaurus ST-1 [Human leukemia] (CVCL_0G05)

[Text version]

Cell line name ST-1 [Human leukemia]
Synonyms ST1
Accession CVCL_0G05
Resource Identification Initiative To cite this cell line use: ST-1 [Human leukemia] (RRID:CVCL_0G05)
Comments Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line

PubMed=9172809; DOI=10.3109/10428199609093442
Yamada Y., Ohmoto Y., Hata T., Yamamura M., Murata K., Tsukasaki K., Kohno T., Chen Y., Kamihira S., Tomonaga M.
Features of the cytokines secreted by adult T cell leukemia (ATL) cells.
Leuk. Lymphoma 21:443-447(1996)

PubMed=9596675; DOI=10.1182/blood.V91.11.4265
Yamada Y., Sugawara K., Hata T., Tsuruta K., Moriuchi R., Maeda T., Atogami S., Murata K., Fujimoto K., Kohno T., Tsukasaki K., Tomonaga M., Hirakata Y., Kamihira S.
Interleukin-15 (IL-15) can replace the IL-2 signal in IL-2-dependent adult T-cell leukemia (ATL) cell lines: expression of IL-15 receptor alpha on ATL cells.
Blood 91:4265-4272(1998)

PubMed=10190897; DOI=10.1084/jem.189.7.1063
Maeda T., Yamada Y., Moriuchi R., Sugahara K., Tsuruda K., Joh T., Atogami S., Tsukasaki K., Tomonaga M., Kamihira S.
Fas gene mutation in the progression of adult T cell leukemia.
J. Exp. Med. 189:1063-1071(1999)

PubMed=10570904; DOI=10.1007/s100380050178
Ariyama Y., Mori T., Shinomiya T., Sakabe T., Fukuda Y., Kanamaru A., Yamada Y., Isobe M., Seto M., Nakamura Y., Inazawa J.
Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines.
J. Hum. Genet. 44:357-363(1999)

PubMed=15638862; DOI=10.1111/j.1365-2141.2004.05289.x
Hasegawa H., Yamada Y., Harasawa H., Tsuji T., Murata K., Sugahara K., Tsuruda K., Ikeda S., Imaizumi Y., Tomonaga M., Masuda M., Takasu N., Kamihira S.
Sensitivity of adult T-cell leukaemia lymphoma cells to tumour necrosis factor-related apoptosis-inducing ligand.
Br. J. Haematol. 128:253-265(2005)

PubMed=19710698; DOI=10.1038/leu.2009.171
Hasegawa H., Yamada Y., Iha H., Tsukasaki K., Nagai K., Atogami S., Sugahara K., Tsuruda K., Ishizaki A., Kamihira S.
Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells.
Leukemia 23:2090-2101(2009)

PubMed=27193821; DOI=10.1111/cas.12971
Hasegawa H., Bissonnette R.P., Gillings M., Sasaki D., Taniguchi H., Kitanosono H., Tsuruda K., Kosai K., Uno N., Morinaga Y., Imaizumi Y., Miyazaki Y., Yanagihara K.
Induction of apoptosis by HBI-8000 in adult T-cell leukemia/lymphoma is associated with activation of Bim and NLRP3.
Cancer Sci. 107:1124-1133(2016)

Cell line databases/resources CGH-DB; 9033-4
Other Wikidata; Q54955728
Entry history
Entry creation10-Apr-2015
Last entry update12-Mar-2020
Version number3