ID   B-THP-1
AC   CVCL_0R19
DR   NIH-ARP; 9940-7
DR   Wikidata; Q54752139
RX   PubMed=10721995;
RX   PubMed=14972530;
CC   Problematic cell line: Misidentified. Originally thought to be THP-1 (PubMed=10721995) but later shown to be a derivative of Raji (PubMed=14972530).
CC   Doubling time: ~20 hours (NIH-ARP).
CC   Sequence variation: MYC-IGH gene fusion (from parent cell line).
CC   Sequence variation: Heterozygous for TP53 p.Arg213Gln (c.638G>A) and p.Tyr234His (c.700T>C) (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
DI   NCIt; C27694; Epstein-Barr virus-related Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0511 ! Raji
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 05-07-19; Version: 8
RX   PubMed=10721995; DOI=10.1016/S0092-8674(00)80694-7;
RA   Geijtenbeek T.B.H., Kwon D.S., Torensma R., van Vliet S.J.,
RA   van Duijnhoven G.C.F., Middel J., Cornelissen L.M.H.A.,
RA   Nottet H.S.L.M., KewalRamani V.N., Littman D.R., Figdor C.G.,
RA   van Kooyk Y.;
RT   "DC-SIGN, a dendritic cell-specific HIV-1-binding protein that
RT   enhances trans-infection of T cells.";
RL   Cell 100:587-597(2000).
RX   PubMed=14972530; DOI=10.1016/j.virol.2003.09.028;
RA   Wu L., Martin T.D., Carrington M., KewalRamani V.N.;
RT   "Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated
RT   HIV transmission.";
RL   Virology 318:17-23(2004).