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Cellosaurus KP-2N (CVCL_0U12)

Cell line name KP-2N
Accession CVCL_0U12
Resource Identification Initiative To cite this cell line use: KP-2N (RRID:CVCL_0U12)
Comments Population: Japanese.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Asp415Glufs*20 (c.1245_1248delCAGA); ClinVar=VCV000142253; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala161Asp (c.482C>A); ClinVar=VCV000422295; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic carcinoma (NCIt: C3850)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3004 (KP-2)
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
Publications

PubMed=2172194; DOI=10.1111/j.1349-7006.1990.tb03336.x
Ikeda Y., Ezaki M., Hayashi I., Yasuda D., Nakayama K., Kono A.
Establishment and characterization of human pancreatic cancer cell lines in tissue culture and in nude mice.
Jpn. J. Cancer Res. 81:987-993(1990)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0U12
Encyclopedic resources Wikidata; Q54900361
Polymorphism and mutation databases Cosmic; 1122346
Cosmic; 1518238
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number10