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Cellosaurus MCF-7/HER2-18 (CVCL_0U80)

[Text version]

Cell line name MCF-7/HER2-18
Synonyms MCF-7 HER2-18; MCF-7/Her2-18; MCF7/HER2-clone 18; MCF7/HER2-18; MCF/HER2-18
Accession CVCL_0U80
Resource Identification Initiative To cite this cell line use: MCF-7/HER2-18 (RRID:CVCL_0U80)
Comments Population: Caucasian.
Transfected with: HGNC; 3430; ERBB2.
Sequence variations Gene deletion; CDKN2A; Zygosity=Homozygous (from parent cell line).
Heterozygous for GATA3 p.Asp336Glyfs*17 (c.1006dupG) (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D3S135816
D5S81812
D7S8208,9
D8S117910,14
D13S31711
D16S53911,12
D18S5114
D21S1130
FGA23,25
Penta D12
Penta E7,12
TH016
TPOX9,12
vWA14,15

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Publications

PubMed=8095168; DOI=10.1007/BF01961241
Benz C.C., Scott G.K., Sarup J.C., Johnson R.M., Tripathy D., Coronado E., Shepard H.M., Osborne C.K.
Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu.
Breast Cancer Res. Treat. 24:85-95(1992)

Cross-references
Biological sample resources BioSample; SAMN03471643
Other Wikidata; Q54904368
Entry history
Entry creation08-Jul-2015
Last entry update12-Jan-2021
Version number10