Cell line name | 22Rv1 | ||||||||||||||||||||||||||||||||
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Synonyms | 22RV1; 22Rv-1; 22rV1; CWR-22rv1; CWR22-Rv1; CWR22R-V1; CWR22-R1; CWR22Rv1; CWR22R | ||||||||||||||||||||||||||||||||
Accession | CVCL_1045 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: 22Rv1 (RRID:CVCL_1045) | ||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: TCGA-110-CL cell line panel. Characteristics: Contains at least 10 integrated copies of xenotropic murine leukemia virus-related virus (XMRV) genome and produces a high titer of the virus (PubMed=19403664; PubMed=30629668). Doubling time: ~49 hours (PubMed=10462204); 55 hours (PubMed=25984343); 63 hours (from cell counting), 94 hours (from absorbance) (DOI=10.5897/IJBMBR2013.0154); 40 hours (ATCC); 40-60 hours (DSMZ); ~41 hours (PBCF); 24.07 hours (https://www.synapse.org/#!Synapse:syn2347014). Microsatellite instability: Instable (MSI-high) (PubMed=23671654; PubMed=31068700; Sanger). Omics: Array-based CGH. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: shRNA library screening. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Prostate. | ||||||||||||||||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Prostate carcinoma (NCIt: C4863) | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Parent: CVCL_3967 (CWR22) Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||
Age at sampling | Adult | ||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP; DSMZ; ECACC; PubMed=14518029; PubMed=25877200; PubMed=27271795; PubMed=31006810 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | https://physics.cancer.gov/docs/bioresource/prostate/NCI-PBCF-CRL2505_22Rv1_SOP-508.pdf https://web.archive.org/web/20160703200709/http://capcelllines.ca:80/details.asp?id=53 https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-524.html | ||||||||||||||||||||||||||||||||
Publications | PubMed=10462204; DOI=10.1007/s11626-999-0115-4 PubMed=12725112; DOI=10.1385/1-59259-372-0:21 PubMed=14518029; DOI=10.1002/pros.10290 PubMed=15486987; DOI=10.1002/pros.20158 PubMed=19403664; DOI=10.1128/JVI.00546-09 PubMed=20164919; DOI=10.1038/nature08768 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=21248069; DOI=10.1158/0008-5472.CAN-10-1998 PubMed=22460905; DOI=10.1038/nature11003 DOI=10.5897/IJBMBR2013.0154 PubMed=23117885; DOI=10.1158/0008-5472.CAN-12-3630 PubMed=23671654; DOI=10.1371/journal.pone.0063056 PubMed=25984343; DOI=10.1038/sdata.2014.35 PubMed=27271795; DOI=10.1002/pros.23190 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=28145883; DOI=10.18632/oncotarget.14850 PubMed=28928128; DOI=10.1158/0008-5472.CAN-17-0320 PubMed=30629668; DOI=10.1371/journal.pone.0210404 PubMed=30787054; DOI=10.1158/1055-9965.EPI-18-1132 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31006810; DOI=10.1093/nar/gkz286 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=31395879; DOI=10.1038/s41467-019-11415-2 PubMed=31978347; DOI=10.1016/j.cell.2019.12.023 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line collections | ATCC; CRL-2505
BCRC; 60545 CCTCC; GDC0288 DSMZ; ACC-438 ECACC; 05092802 KCB; KCB 200731YJ | ||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0001199
CLO; CLO_0001200 CCRID; 3101HUMSCSP5022 CCRID; 3101HUMTCHu100 CCRID; 4201HUM-CCTCC00288 Cell_Model_Passport; SIDM00499 Cosmic-CLP; 924100 DepMap; ACH-000956 IGRhCellID; 22Rv1 LINCS_LDP; LCL-1145 Lonza; 1442 | ||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0002999 | ||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03471600
BioSample; SAMN03472052 BioSample; SAMN05292447 BioSample; SAMN07710012 BioSample; SAMN07710013 BioSample; SAMN07710014 BioSample; SAMN07710015 BioSample; SAMN07710016 BioSample; SAMN07710017 BioSample; SAMN07710018 BioSample; SAMN10988315 ENCODE; ENCBS070BKF ENCODE; ENCBS383WOY ENCODE; ENCBS596KKM ENCODE; ENCBS626QQL ENCODE; ENCBS737IZN ENCODE; ENCBS822DIG | ||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308004
ChEMBL-Targets; CHEMBL612657 GDSC; 924100 PharmacoDB; 22RV1_12_2019 | ||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54583380 | ||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002095 | ||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM91926 GEO; GSM525793 GEO; GSM648815 GEO; GSM827396 GEO; GSM886837 GEO; GSM887900 GEO; GSM1374375 GEO; GSM1633317 GEO; GSM1633318 GEO; GSM1633319 GEO; GSM1669565 | ||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 924100
Cosmic; 1075276 Cosmic; 1028699 Cosmic; 1071480 Cosmic; 1172629 Cosmic; 1330911 Cosmic; 1689707 Cosmic; 1995323 Cosmic; 2537791 Cosmic; 2580126 Cosmic; 2651766 Cosmic; 2669170 IARC_TP53; 18887 LiGeA; CCLE_229 Progenetix; CVCL_1045 | ||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||
Last entry update | 16-Dec-2021 | ||||||||||||||||||||||||||||||||
Version number | 39 |