Cellosaurus A101D (CVCL_1057)

Cell line name A101D
Synonyms A-101D
Accession CVCL_1057
Resource Identification Initiative To cite this cell line use: A101D (RRID:CVCL_1057)
Comments Part of: BRAF genetic alteration cell panel (ATCC TCP-1032).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Microsatellite instability: Stable (MSS) (Sanger).
Sequence variation: Heterozygous for BRAF p.Val600Glu (ATCC).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0331 ! Hs 294T
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX
CSF1PO11
D13S31711,12
D16S53912
D5S81812
D7S82010
TH018,9.3
TPOX8,11
vWA16,18
Publications

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-7898
Cell line databases/resources CCLE; A101D_SKIN
Cosmic-CLP; 910921
GDSC; 910921
IGRhCellID; A101D
LINCS_LDP; LCL-1267
Ontologies CLO; CLO_0001551
EFO; EFO_0002100
Biological sample resources BioSample; SAMN03471114
Chemistry resources ChEMBL-Cells; CHEMBL3308182
ChEMBL-Targets; CHEMBL2366306
Gene expression databases GEO; GSM886849
GEO; GSM887913
GEO; GSM1669576
Polymorphism and mutation databases Cosmic; 687429
Cosmic; 910921
Cosmic; 1155279
Cosmic; 1995326