Cell line name | A-253 | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | A 253; A253 | ||||||||||||||||||
Accession | CVCL_1060 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: A-253 (RRID:CVCL_1060) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Salivary gland; submandibular gland. | ||||||||||||||||||
Sequence variations |
| ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||
Disease | Submandibular gland squamous cell carcinoma (NCIt: C5943) Squamous cell carcinoma of salivary glands (ORDO: Orphanet_500481) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
| ||||||||||||||||||
Hierarchy | Children:
| ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 54Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP; PubMed=29923277 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=4357758; DOI=10.1093/jnci/51.5.1417 PubMed=327080; DOI=10.1093/jnci/59.1.221 PubMed=833871; DOI=10.1093/jnci/58.2.209 PubMed=6256643; DOI=10.1038/288724a0 PubMed=22282976; DOI=10.1093/carcin/1.1.21 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=3138611; DOI=10.1177/019459988809800603 DOI=10.1016/B978-0-12-333530-2.50007-1 PubMed=22460905; DOI=10.1038/nature11003 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=29923277; DOI=10.1111/odi.12920 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ATCC; CRL-7902 - Discontinued
ATCC; HTB-41 BCRC; 60367 BCRJ; 0322 IZSLER; BS TCL 199 KCLB; 30041 - Discontinued | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0001569
CLO; CLO_0001570 Cell_Model_Passport; SIDM00796 Cosmic-CLP; 906794 DepMap; ACH-000740 LINCS_LDP; LCL-2034 TOKU-E; 462 | ||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0003206 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471117
BioSample; SAMN10988034 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307893
ChEMBL-Targets; CHEMBL614255 GDSC; 906794 PharmacoDB; A253_39_2019 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54605985 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM422867 GEO; GSM886852 GEO; GSM887917 GEO; GSM1669580 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 688036
Cosmic; 906794 Cosmic; 921831 Cosmic; 1017790 Cosmic; 1006471 Cosmic; 1041671 Cosmic; 1995330 Cosmic; 2646649 IARC_TP53; 21160 LiGeA; CCLE_437 Progenetix; CVCL_1060 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD002486 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 16-Dec-2021 | ||||||||||||||||||
Version number | 34 |