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Cellosaurus A3 (CVCL_1061)

[Text version]

Cell line name A3
Synonyms Jurkat clone A3
Accession CVCL_1061
Resource Identification Initiative To cite this cell line use: A3 (RRID:CVCL_1061)
Comments Omics: Metabolome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for BAX p.Glu41Argfs*19 (c.121delG) (ClinVar=VCV000009512) and p.Glu41Glyfs*33 (c.121dupG) (ClinVar=VCV000009511) (from parent cell line).
Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).
Heterozygous for INPP5D p.Gln345Ter (c.1033C>T) and c.1097+1065_1097+1112del47 (from parent cell line).
Homozygous for MSH2 p.Arg711Ter (c.2131C>T) (ClinVar=VCV000090903) (from parent cell line).
Homozygous for MSH6 p.Phe1088Serfs*2 (c.3261delC) (ClinVar=VCV000089363) (from parent cell line).
Heterozygous for TP53 p.Arg196Ter (c.586C>T) (ClinVar=VCV000043589) (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0065 (Jurkat)
Children:
CVCL_3724 (I 2.1)CVCL_3725 (I 9.2)CVCL_HF44 (Jurkat-FADD-/-)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S8189
D7S8208,10
D13S3178,11
D16S53911
TH016,9.3
TPOX8,10
vWA17,18

Run an STR similarity search on this cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=664
Publications

PubMed=8972182; DOI=10.1128/MCB.17.1.24
Juo P., Kuo C.J., Reynolds S.E., Konz R.F., Raingeaud J., Davis R.J., Biemann H.P., Blenis J.
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases.
Mol. Cell. Biol. 17:24-35(1997)

PubMed=10616904
Juo P., Woo M.S.-A., Kuo C.J., Signorelli P., Biemann H.P., Hannun Y.A., Blenis J.
FADD is required for multiple signaling events downstream of the receptor Fas.
Cell Growth Differ. 10:797-804(1999)

Cross-references
Cell line collections ATCC; CRL-2570
BCRC; 60485
KCB; KCB 201084YJ
Cell line databases/resources CCRID; 3131C0001000700096
Cell_Model_Passport; SIDM01243
LINCS_LDP; LCL-1026
Ontologies BTO; BTO:0001342
CLO; CLO_0001577
Biological sample resources BioSample; SAMN03471678
Metabolomic databases MetaboLights; MTBLS226
Other Wikidata; Q54606726
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number20