Cell line name | ACN | ||||||||||||||||||||
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Accession | CVCL_1068 | ||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: ACN (RRID:CVCL_1068) | ||||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||||
Sequence variations | Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (CCLE; Cosmic-CLP).Heterozygous for PTEN p.Asn184fs*6 (c.545_546insA) (CCLE; Cosmic-CLP).Homozygous for TP53 p.Phe113Ser (c.338T>C) (ClinVar=VCV000823709) (CCLE; Cosmic-CLP). | ||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635) Derived from metastatic site: Bone marrow. | ||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||||
Age at sampling | 3Y3M | ||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; ICLC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||
Publications | PubMed=2467885; DOI=10.1002/ijc.2910430421 PubMed=1354203; DOI=10.1002/ijc.2910520116 DOI=10.1007/0-306-46872-7_2 PubMed=20164919; DOI=10.1038/nature08768 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||||
Cross-references | |||||||||||||||||||||
Cell line collections | ICLC; HTL96020 | ||||||||||||||||||||
Cell line databases/resources | CLDB; cl239
CCLE; ACN Cell_Model_Passport; SIDM00057 Cosmic-CLP; 906803 DepMap; ACH-002389 LINCS_LDP; LCL-1982 | ||||||||||||||||||||
Ontologies | CLO; CLO_0001655 | ||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308148
ChEMBL-Targets; CHEMBL2366195 GDSC; 906803 PharmacoDB; ACN_55_2019 | ||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM1669594 | ||||||||||||||||||||
Other | Wikidata; Q54608539 | ||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 906803
IARC_TP53; 21170 | ||||||||||||||||||||
Entry history | |||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||||
Version number | 26 |