Cellosaurus ATN-1 (CVCL_1073)

Cell line name ATN-1
Synonyms ATN1
Accession CVCL_1073
Resource Identification Initiative To cite this cell line use: ATN-1 (RRID:CVCL_1073)
Comments Part of: COSMIC cell lines project.
Doubling time: ~24 hours (PubMed=3260813).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Derived from sampling site: Peripheral blood.
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB


PubMed=3260813; DOI=10.1016/0165-4608(88)90171-9
Naoe T., Akao Y., Yamada K., Utsumi K.R., Koike K., Shamoto M., Koie K., Kurosawa Y., Kato K., Abe M., Shiku H.
Cytogenetic characterization of a T-cell line, ATN-1, derived from adult T-cell leukemia cells.
Cancer Genet. Cytogenet. 34:77-88(1988)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections RCB; RCB1440
Cell line databases/resources Cosmic-CLP; 910687
GDSC; 910687
Ontologies CLO; CLO_0050985
Biological sample resources BioSample; SAMN03472143
Chemistry resources ChEMBL-Cells; CHEMBL3308183
ChEMBL-Targets; CHEMBL2366277
Gene expression databases GEO; GSM1669604
Polymorphism and mutation databases Cosmic; 910687