ID   ATN-1
AC   CVCL_1073
SY   ATN1
DR   CLO; CLO_0050985
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   BioSample; SAMN03472143
DR   CCLE; ATN1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
DR   Cell_Model_Passport; SIDM00233
DR   ChEMBL-Cells; CHEMBL3308183
DR   ChEMBL-Targets; CHEMBL2366277
DR   Cosmic; 910687
DR   Cosmic-CLP; 910687
DR   DepMap; ACH-002058
DR   GDSC; 910687
DR   GEO; GSM1669604
DR   LINCS_LDP; LCL-1025
DR   PharmacoDB; ATN1_68_2019
DR   RCB; RCB1440
DR   Wikidata; Q54751288
RX   PubMed=3260813;
RX   PubMed=9738977;
RX   PubMed=20164919;
RX   PubMed=27397505;
RX   PubMed=30894373;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: COSMIC cell lines project.
CC   Doubling time: ~24 hours (PubMed=3260813).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Omics: Deep exome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0%; Native American=0.05%; East Asian, North=78.58%; East Asian, South=17.98%; South Asian=1.43%; European, North=0%; European, South=1.95% (PubMed=30894373).
CC   Derived from sampling site: Peripheral blood.
ST   Source(s): Cosmic-CLP; RCB
ST   Amelogenin: X,Y
ST   CSF1PO: 9,11
ST   D13S317: 11,12
ST   D16S539: 11
ST   D5S818: 10,13
ST   D7S820: 8
ST   TH01: 9
ST   TPOX: 9
ST   vWA: 14,18
DI   NCIt; C9142; Adult T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 12-03-20; Version: 27
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RX   PubMed=3260813; DOI=10.1016/0165-4608(88)90171-9;
RA   Naoe T., Akao Y., Yamada K., Utsumi K.R., Koike K., Shamoto M.,
RA   Koie K., Kurosawa Y., Kato K., Abe M., Shiku H.;
RT   "Cytogenetic characterization of a T-cell line, ATN-1, derived from
RT   adult T-cell leukemia cells.";
RL   Cancer Genet. Cytogenet. 34:77-88(1988).
//
RX   PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x;
RA   Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T.,
RA   Aizawa Y., Ueda R., Seto M.;
RT   "Expression of the TCL1 gene at 14q32 in B-cell malignancies but not
RT   in adult T-cell leukemia.";
RL   Jpn. J. Cancer Res. 89:712-718(1998).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M.,
RA   Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M.,
RA   Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A.,
RA   Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//