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Cellosaurus BALL-1 (CVCL_1075)

Cell line name BALL-1
Synonyms Ball-1; Ball 1; BALL1; B-cell Acute Lymphoblastic Leukemia-1
Accession CVCL_1075
Resource Identification Initiative To cite this cell line use: BALL-1 (RRID:CVCL_1075)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Doubling time: 80 hours (in RPMI-1640+20% HCS), 66 hours (in RPMI-1640+20% FCS) (PubMed=195075); ~48-72 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_U321 (JDB1)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; JCRB; RCB; TKG

Markers:
AmelogeninX,Y (Cosmic-CLP; DSMZ; RCB)
X (JCRB; TKG)
CSF1PO10,12
D13S3179,12
D16S5399
D5S81810,13 (Cosmic-CLP; JCRB; TKG)
10,12,13 (RCB)
D7S82010,12
TH017,9
TPOX8,11
vWA14,18
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=195075; DOI=10.1093/jnci/59.1.93
Hiraki S., Miyoshi I., Masuji H., Kubonishi I., Matsuda Y.
Establishment of an Epstein-Barr virus-determined nuclear antigen-negative human B-cell line from acute lymphoblastic leukemia.
J. Natl. Cancer Inst. 59:93-94(1977)

PubMed=197412; DOI=10.1038/267843a0
Miyoshi I., Hiraki S., Tsubota T., Kubonishi I., Matsuda Y., Nakayama T., Kishimoto H., Kimura I., Masuji H.
Human B cell, T cell and null cell leukaemic cell lines derived from acute lymphoblastic leukaemias.
Nature 267:843-844(1977)

CLPUB00015
Nakamura K.
Studies on human leukemic B-cell line, Part I. Establishment and characterization of human leukemic B-cell line (BALL-1).
Okayama Igakkai Zasshi 92:763-773(1980)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=8156010; DOI=10.1159/000236736
Yoshida N., Ueno M., Saita N., Hirashima M.
A B cell lymphoma line, BALL-1 stimulates T cells to produce a unique eosinophil chemotactic factor.
Int. Arch. Allergy Immunol. 104:9-11(1994)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections DSMZ; ACC-742
JCRB; JCRB0071
KCB; KCB 94007YJ
RCB; RCB0256
RCB; RCB1882
TKG; TKG 0467
Cell line databases/resources CCLE; BALL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 910705
GDSC; 910705
LINCS_LDP; LCL-1005
Ontologies BTO; BTO:0001148
CLO; CLO_0051004
CLO; CLO_0051005
Biological sample resources BioSample; SAMN03471059
BioSample; SAMN03472350
Chemistry resources ChEMBL-Cells; CHEMBL3308839
ChEMBL-Targets; CHEMBL2366269
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827223
GEO; GSM1669606
Other Wikidata; Q54753112
Polymorphism and mutation databases Cosmic; 910705
Cosmic; 919134
Cosmic; 999755
Cosmic; 999762
Cosmic; 1150902