Cell line name | BB30-HNC | ||||||||||||||||||
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Synonyms | BB30 HNC; BB30HNC; BB30-SCCHN | ||||||||||||||||||
Accession | CVCL_1076 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: BB30-HNC (RRID:CVCL_1076) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||
Sequence variations | Heterozygous for SMAD4 p.Ser144Ter (c.431C>G) (CCLE; Cosmic-CLP).Heterozygous for TP53 c.96+2T>G; Note=Splice donor mutation (CCLE; Cosmic-CLP).Heterozygous for TP53 p.Ser183Ter (c.548C>A) (CCLE; Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Head and neck squamous cell carcinoma (NCIt: C34447) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Originate from same individual | CVCL_VU86 ! BB30-PBL | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | Age unspecified | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=20164919; DOI=10.1038/nature08768 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line databases/resources | CCLE; BB30HNC_UPPER_AERODIGESTIVE_TRACT
Cell_Model_Passport; SIDM00172 Cosmic-CLP; 753531 DepMap; ACH-002212 LINCS_LDP; LCL-1573 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308548
ChEMBL-Targets; CHEMBL2366271 GDSC; 753531 PharmacoDB; BB30HNC_74_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM1669607 | ||||||||||||||||||
Other | Wikidata; Q54795061 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 753531
Cosmic; 1995343 IARC_TP53; 21186 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||
Version number | 26 |