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Cellosaurus BB65-RCC (CVCL_1078)

[Text version]

Cell line name BB65-RCC
Synonyms BB65 RCC; BB65RCC; BB65
Accession CVCL_1078
Resource Identification Initiative To cite this cell line use: BB65-RCC (RRID:CVCL_1078)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Heterozygous for TP53 p.Arg248Trp (c.742C>T) (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.53
Native American1.94
East Asian, North1.65
East Asian, South0
South Asian0.38
European, North59.69
European, South35.82
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6F66 ! BB65-EBV
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,14
D7S82011,12
D13S3178
D16S53912,13
TH016,7
TPOX8
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=10074909; DOI=10.1002/(SICI)1097-0215(19990315)80:6<799::AID-IJC1>3.0.CO;2-U
Dumas F., Gala J.-L., Berteau P., Brasseur F., Eschwege P., Paradis V., Lacour B., Philippe M., Loric S.
Molecular expression of PSMA mRNA and protein in primary renal tumors.
Int. J. Cancer 80:799-803(1999)

PubMed=14762065; DOI=10.1101/gr.2012304
Bignell G.R., Huang J., Greshock J., Watt S., Butler A., West S., Grigorova M., Jones K.W., Wei W., Stratton M.R., Futreal P.A., Weber B., Shapero M.H., Wooster R.
High-resolution analysis of DNA copy number using oligonucleotide microarrays.
Genome Res. 14:287-295(2004)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; BB65RCC_KIDNEY
Cell_Model_Passport; SIDM00191
Cosmic-CLP; 753533
DepMap; ACH-002090
LINCS_LDP; LCL-1763
Chemistry resources ChEMBL-Cells; CHEMBL3308283
ChEMBL-Targets; CHEMBL2366247
GDSC; 753533
PharmacoDB; BB65RCC_76_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1669609
Other Wikidata; Q54795073
Polymorphism and mutation databases Cosmic; 753533
IARC_TP53; 21188
IARC_TP53; 26919
Entry history
Entry creation04-Apr-2012
Last entry updated19-Dec-2019
Version number24