Cellosaurus BEN (CVCL_1082)

Cell line name BEN
Accession CVCL_1082
Resource Identification Initiative To cite this cell line use: BEN (RRID:CVCL_1082)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~40-50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Misspelling: 1BEN; In Cosmic 1188583.
Disease Non-small cell lung carcinoma (NCIt: C2926)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX (DSMZ)
X,Y (Cosmic-CLP; PubMed=25877200)
CSF1PO10
D13S31712
D16S53911
D18S5115,16,18
D21S1130
D3S135814
D5S81812
D7S82012
D8S11798
FGA21,25
Penta D12
Penta E20
TH016
TPOX8,9 (Cosmic-CLP; DSMZ)
9 (PubMed=25877200)
vWA15
Publications

PubMed=1233082; DOI=10.1038/bjc.1975.237
Ellison M., Woodhouse D., Hillyard C., Dowsett M., Coombes R.C., Gilby E.D., Greenberg P.B., Neville A.M.
Immunoreactive calcitonin production by human lung carcinoma cells in culture.
Br. J. Cancer 32:373-379(1975)

PubMed=10908148; DOI=10.1038/labinvest.3780108
Speicher M.R., Petersen S., Uhrig S., Jentsch I., Fauth C., Eils R., Petersen I.
Analysis of chromosomal alterations in non-small cell lung cancer by multiplex-FISH, comparative genomic hybridization, and multicolor bar coding.
Lab. Invest. 80:1031-1041(2000)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-254
Cell line databases/resources CLDB; cl414
CCLE; BEN_LUNG
Cosmic-CLP; 753534
GDSC; 753534
LINCS_LDP; LCL-1602
Ontologies BTO; BTO:0000253
CLO; CLO_0001926
EFO; EFO_0006537
Biological sample resources BioSample; SAMN03473096
BioSample; SAMN03473332
Chemistry resources ChEMBL-Cells; CHEMBL3308709
ChEMBL-Targets; CHEMBL1075395
Gene expression databases GEO; GSM784239
GEO; GSM827594
GEO; GSM886878
GEO; GSM887943
GEO; GSM1669616
Polymorphism and mutation databases Cosmic; 753534
Cosmic; 1188583
Cosmic; 1995344