Cellosaurus BHT-101 (CVCL_1085)

Cell line name BHT-101
Synonyms BHT101
Accession CVCL_1085
Resource Identification Initiative To cite this cell line use: BHT-101 (RRID:CVCL_1085)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~2-3 days (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Thyroid gland undifferentiated (anaplastic) carcinoma (NCIt: C3878)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=18713817

Markers:
AmelogeninX
CSF1PO12,13 (Cosmic-CLP)
12 (DSMZ)
D13S31712
D16S5399,11
D18S5112,15
D21S1129,32.2
D3S135816,17
D5S81810,11
D7S82010,11
D8S117913,14,15
FGA18,24
TH019,9.3
TPOX8
vWA19 (Cosmic-CLP; DSMZ)
18,19 (PubMed=18713817)
Publications

PubMed=8099464; DOI=10.1007/BF02899271
Palyi I., Peter I., Daubner D., Vincze B., Lorincz I.
Establishment, characterization and drug sensitivity of a new anaplastic thyroid carcinoma cell line (BHT-101).
Virchows Arch. B. Cell. Pathol. Incl. Mol. Pathol. 63:263-269(1993)

PubMed=18713817; DOI=10.1210/jc.2008-1102
Schweppe R.E., Klopper J.P., Korch C., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A., Smallridge R.C., Haugen B.R.
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-279
Cell line databases/resources CCLE; BHT101_THYROID
Cosmic-CLP; 906696
GDSC; 906696
IGRhCellID; BHT101
LINCS_LDP; LCL-1688
Ontologies BTO; BTO:0002274
CLO; CLO_0001974
EFO; EFO_0002116
Biological sample resources BioSample; SAMN03473340
Chemistry resources ChEMBL-Cells; CHEMBL3308096
ChEMBL-Targets; CHEMBL1075398
Gene expression databases GEO; GSM886881
GEO; GSM887946
GEO; GSM1669619
Polymorphism and mutation databases Cosmic; 891255
Cosmic; 906696
Cosmic; 1162841
Cosmic; 1239963
Cosmic; 2054079
Cosmic; 2613250