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Cellosaurus BPH-1 (CVCL_1091)

[Text version]

Cell line name BPH-1
Synonyms BPH1
Accession CVCL_1091
Resource Identification Initiative To cite this cell line use: BPH-1 (RRID:CVCL_1091)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: ~50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Benign prostatic hyperplasia (NCIt: C2897)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4753 (BPH-1-CAFTD-01)CVCL_4755 (BPH-1-CAFTD-03)CVCL_4757 (BPH-1-CAFTD-05)
CVCL_4759 (BPH-1-CAFTD-07)CVCL_4751 (BPH-1 TETD-A)CVCL_4752 (BPH-1 TETD-B)
Sex of cell Male
Age at sampling 68Y
Category Transformed cell line
STR profile Source(s): Cosmic-CLP; DSMZ


Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20150602153427/http://capcelllines.ca:80/details.asp?id=132

PubMed=7535634; DOI=10.1007/BF02631333
Hayward S.W., Dahiya R., Cunha G.R., Bartek J., Deshpande N., Narayan P.
Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1.
In Vitro Cell. Dev. Biol. Anim. 31:14-24(1995)

Phillips J.L., Hayward S.W., Wang Y., Vasselli J., Pavlovich C.P., Padilla-Nash H.M., Pezullo J.R., Ghadimi B.M., Grossfeld G.D., Rivera A., Linehan W.M., Cunha G.R., Ried T.
The consequences of chromosomal aneuploidy on gene expression profiles in a cell line model for prostate carcinogenesis.
Cancer Res. 61:8143-8149(2001)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections DSMZ; ACC-143
ICLC; HTL11006
Cell line databases/resources CLDB; cl7219
Cell_Model_Passport; SIDM00964
Cosmic-CLP; 924105
GDSC; 924105
LINCS_HMS; 50005
Ontologies BTO; BTO:0001323
CLO; CLO_0002022
Biological sample resources BioSample; SAMN03473417
Chemistry resources ChEMBL-Cells; CHEMBL3308186
ChEMBL-Targets; CHEMBL2366131
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827571
GEO; GSM1374405
GEO; GSM1669628
Other Wikidata; Q54798059
Polymorphism and mutation databases Cosmic; 924105
Cosmic; 1995347