Cellosaurus BPH-1 (CVCL_1091)

Cell line name BPH-1
Synonyms BPH1
Accession CVCL_1091
Resource Identification Initiative To cite this cell line use: BPH-1 (RRID:CVCL_1091)
Comments Doubling time: ~50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Disease Benign prostatic hyperplasia (NCIt: C2897)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_4753 (BPH-1-CAFTD-01); CVCL_4755 (BPH-1-CAFTD-03); CVCL_4757 (BPH-1-CAFTD-05); CVCL_4759 (BPH-1-CAFTD-07); CVCL_4751 (BPH-1 TETD-A); CVCL_4752 (BPH-1 TETD-B)
Sex of cell Male
Category Transformed cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,12
D13S31711,12
D16S5399
D5S81811,12
D7S82010,11
TH016,7
TPOX8,12
vWA17
Web pages http://capcelllines.ca/details.asp?id=132
Publications

PubMed=7535634; DOI=10.1007/BF02631333
Hayward S.W., Dahiya R., Cunha G.R., Bartek J., Deshpande N., Narayan P.
Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1.
In Vitro Cell. Dev. Biol. Anim. 31:14-24(1995)

PubMed=11719443
Phillips J.L., Hayward S.W., Wang Y., Vasselli J., Pavlovich C.P., Padilla-Nash H.M., Pezullo J.R., Ghadimi B.M., Grossfeld G.D., Rivera A., Linehan W.M., Cunha G.R., Ried T.
The consequences of chromosomal aneuploidy on gene expression profiles in a cell line model for prostate carcinogenesis.
Cancer Res. 61:8143-8149(2001)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-143
ICLC; HTL11006
Cell line databases/resources CLDB; cl7219
Cosmic-CLP; 924105
GDSC; 924105
IGRhCellID; BPH1
LINCS_HMS; 50005
LINCS_LDP; LCL-2095
Lonza; 541
SKY/M-FISH/CGH; 1510
Ontologies BTO; BTO:0001323
CLO; CLO_0002022
Biological sample resources BioSample; SAMN03473417
Chemistry resources ChEMBL-Cells; CHEMBL3308186
ChEMBL-Targets; CHEMBL2366131
Gene expression databases GEO; GSM827571
GEO; GSM1374405
GEO; GSM1669628
Polymorphism and mutation databases Cosmic; 924105
Cosmic; 1995347