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Cellosaurus CAL-39 (CVCL_1109)

[Text version]

Cell line name CAL-39
Synonyms CAL 39; CAL39; Centre Antoine Lacassagne-39
Accession CVCL_1109
Resource Identification Initiative To cite this cell line use: CAL-39 (RRID:CVCL_1109)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 30 hours, at 34th passage (PubMed=21573363); ~50-70 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Vulva.
Sequence variations Homozygous for FAT1 p.Arg2597Ter (c.7789C>T) (CCLE; Cosmic-CLP).
Homozygous for TP53 p.Pro151His (c.452C>A) (ClinVar=VCV000376639) (CCLE; Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0.78
East Asian, North0
East Asian, South1.64
South Asian9.08
European, North26.43
European, South59.19
Disease Vulvar squamous cell carcinoma (NCIt: C4052)
Vulvar squamous cell carcinoma (ORDO: Orphanet_494448)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ


Run an STR similarity search on this cell line

PubMed=21573363; DOI=10.3892/ijo.3.2.293
Gioanni J., Grosgeorge J., Zanghellini E., Mazeau C., Gaudray P., Ettore F., Formento P., Demard F.
Characterization of CAL39, a new human cell-line derived from a vulvar squamous-cell carcinoma.
Int. J. Oncol. 3:293-297(1993)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cell line collections DSMZ; ACC-187
Cell line databases/resources CLDB; cl630
Cell_Model_Passport; SIDM00935
Cosmic-CLP; 924107
DepMap; ACH-002091
Ontologies CLO; CLO_0002184
Biological sample resources BioSample; SAMN03473368
Chemistry resources ChEMBL-Cells; CHEMBL3308716
ChEMBL-Targets; CHEMBL1075410
GDSC; 924107
PharmacoDB; CAL39_171_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1669651
Other Wikidata; Q54808399
Polymorphism and mutation databases Cosmic; 924107
Cosmic; 1995358
IARC_TP53; 27146
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number28