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Cellosaurus CAL-72 (CVCL_1113)

[Text version]

Cell line name CAL-72
Synonyms CAL 72; CAL72; Cal72; Centre Antoine Lacassagne-72
Accession CVCL_1113
Resource Identification Initiative To cite this cell line use: CAL-72 (RRID:CVCL_1113)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 66 hours, at 17th passage (PubMed=10389764); ~40-50 hours (DSMZ).
Microsatellite instability: Instable (MSI-low) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African67.94
Native American0.09
East Asian, North1.27
East Asian, South0
South Asian24.79
European, North0
European, South5.91
Disease Osteosarcoma (NCIt: C9145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81813
D7S82011
D13S3178
D16S53910
TH018
TPOX11
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=10389764; DOI=10.1002/(SICI)1097-0215(19990719)82:2<282::AID-IJC20>3.0.CO;2-R
Rochet N., Dubousset J., Mazeau C., Zanghellini E., Farges M.-F., Stora de Novion H., Chompret A., Delpech B., Cattan N., Frenay M., Gioanni J.
Establishment, characterisation and partial cytokine expression profile of a new human osteosarcoma cell line (CAL 72).
Int. J. Cancer 82:282-285(1999)

PubMed=12631258; DOI=10.1034/j.1600-0609.2003.02766.x
Rochet N., Leroy P., Far D.F., Ollier L., Loubat A., Rossi B.
CAL72: a human osteosarcoma cell line with unique effects on hematopoietic cells.
Eur. J. Haematol. 70:43-52(2003)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections DSMZ; ACC-439
Cell line databases/resources CCLE; CAL72_BONE
Cell_Model_Passport; SIDM00930
Cosmic-CLP; 906827
DepMap; ACH-001715
GDSC; 906827
LINCS_LDP; LCL-1419
Ontologies BTO; BTO:0002089
CLO; CLO_0002188
Biological sample resources BioSample; SAMN03473545
Chemistry resources ChEMBL-Cells; CHEMBL3308718
ChEMBL-Targets; CHEMBL1075414
PharmacoDB; CAL72_175_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM320825
GEO; GSM1669655
Other Wikidata; Q54808412
Polymorphism and mutation databases Cosmic; 906827
Cosmic; 1074399
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number25