Cellosaurus CAL-72 (CVCL_1113)

Cell line name CAL-72
Synonyms CAL 72; CAL72; Cal72
Accession CVCL_1113
Resource Identification Initiative To cite this cell line use: CAL-72 (RRID:CVCL_1113)
Comments Doubling time: 66 hours, at 17th passage (PubMed=10389764); ~40-50 hours (DSMZ).
Microsatellite instability: Instable (MSI-low) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Osteosarcoma (NCIt: C9145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,11
D13S3178
D16S53910
D5S81813
D7S82011
TH018
TPOX11
vWA15,17
Publications

PubMed=10389764; DOI=10.1002/(SICI)1097-0215(19990719)82:2<282::AID-IJC20>3.0.CO;2-R
Rochet N., Dubousset J., Mazeau C., Zanghellini E., Farges M.-F., Stora de Novion H., Chompret A., Delpech B., Cattan N., Frenay M., Gioanni J.
Establishment, characterisation and partial cytokine expression profile of a new human osteosarcoma cell line (CAL 72).
Int. J. Cancer 82:282-285(1999)

PubMed=12631258; DOI=10.1034/j.1600-0609.2003.02766.x
Rochet N., Leroy P., Far D.F., Ollier L., Loubat A., Rossi B.
CAL72: a human osteosarcoma cell line with unique effects on hematopoietic cells.
Eur. J. Haematol. 70:43-52(2003)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-439
Cell line databases/resources Cosmic-CLP; 906827
GDSC; 906827
LINCS_LDP; LCL-1419
Ontologies BTO; BTO:0002089
CLO; CLO_0002188
Biological sample resources BioSample; SAMN03473545
Chemistry resources ChEMBL-Cells; CHEMBL3308718
ChEMBL-Targets; CHEMBL1075414
Gene expression databases GEO; GSM320825
GEO; GSM1669655
Polymorphism and mutation databases Cosmic; 906827
Cosmic; 1074399