Cell line name | CAS-1 | ||||||||||||||||||
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Synonyms | CAS1 | ||||||||||||||||||
Accession | CVCL_1117 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: CAS-1 (RRID:CVCL_1117) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: TCGA-110-CL cell line panel. Population: Caucasian. Doubling time: 60 hours (PubMed=25984343). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: shRNA library screening. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Brain. | ||||||||||||||||||
Sequence variations | Homozygous for TP53 p.Arg248Trp (c.742C>T) (ClinVar=VCV000012347) (Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||
Age at sampling | 63Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=12635657; DOI=10.1023/A:1020630214549 PubMed=20164919; DOI=10.1038/nature08768 PubMed=22460905; DOI=10.1038/nature11003 PubMed=25984343; DOI=10.1038/sdata.2014.35 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=31395879; DOI=10.1038/s41467-019-11415-2 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ICLC; HTL97009 | ||||||||||||||||||
Cell line databases/resources | CLDB; cl4963
CCLE; CAS1_CENTRAL_NERVOUS_SYSTEM Cell_Model_Passport; SIDM00212 Cosmic-CLP; 910943 DepMap; ACH-000464 LINCS_LDP; LCL-1369 | ||||||||||||||||||
Ontologies | CLO; CLO_0002200 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN10987869 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308187
ChEMBL-Targets; CHEMBL2366100 GDSC; 910943 PharmacoDB; CAS1_187_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM886922 GEO; GSM887988 GEO; GSM1669666 | ||||||||||||||||||
Other | Wikidata; Q54808612 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 910943
Cosmic; 2367510 Cosmic; 2516014 IARC_TP53; 21216 LiGeA; CCLE_412 Progenetix; CVCL_1117 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 26 |