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Cellosaurus CCF-STTG1 (CVCL_1118)

[Text version]

Cell line name CCF-STTG1
Synonyms CCFSTTG1; STTG1
Accession CVCL_1118
Resource Identification Initiative To cite this cell line use: CCF-STTG1 (RRID:CVCL_1118)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: PTEN genetic alteration cell panel (ATCC TCP-1030).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Discontinued: TKG; TKG 0581; true.
Sequence variations Has no IDH1 mutation (PubMed=19435942).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.55
Native American0
East Asian, North1.13
East Asian, South0
South Asian0.6
European, North60.84
European, South36.87
Disease Astrocytoma (NCIt: C60781)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): ATCC; CLS; Cosmic-CLP; PubMed=25877200; RCB

Markers:
AmelogeninX
CSF1PO12
D2S133820,26
D3S135816,17
D5S81812,13
D7S82010,11
D8S117913,14
D13S31711,13
D16S53911,12
D18S5115
D19S43315.2,16
D21S1128,29
FGA20,22
Penta D11,13
Penta E10
TH017,8
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=3877740; DOI=10.1016/0165-5728(85)90005-0
Barna B.P., Chou S.M., Jacobs B., Ransohoff R.M., Hahn J.F., Bay J.W.
Enhanced DNA synthesis of human glial cells exposed to human leukocyte products.
J. Neuroimmunol. 10:151-158(1985)

PubMed=1404494; DOI=10.1002/jnr.490320212
Krul E.S., Tang J.
Secretion of apolipoprotein E by an astrocytoma cell line.
J. Neurosci. Res. 32:227-238(1992)

PubMed=19435942; DOI=10.1215/15228517-2009-025
Ichimura K., Pearson D.M., Kocialkowski S., Backlund L.M., Chan R., Jones D.T.W., Collins V.P.
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas.
Neuro-oncol. 11:341-347(2009)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ATCC; CRL-1718
CLS; 300388/p721_CCF-STTG1
ECACC; 90021502
IZSLER; BS TCL 125
RCB; RCB1977 - Discontinued
TKG; TKG 0581
Cell line databases/resources CLDB; cl669
CLDB; cl5177
CCLE; CCFSTTG1_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00131
Cosmic-CLP; 906823
GDSC; 906823
IGRhCellID; CCFSTTG1
LINCS_LDP; LCL-1394
Ontologies BTO; BTO:0003863
CLO; CLO_0002329
EFO; EFO_0002127
Biological sample resources BioSample; SAMN01821545
BioSample; SAMN03470976
Chemistry resources ChEMBL-Cells; CHEMBL3308795
ChEMBL-Targets; CHEMBL1075419
Gene expression databases ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM326233
GEO; GSM886923
GEO; GSM887989
GEO; GSM1374443
GEO; GSM1669668
Other Wikidata; Q54808966
Polymorphism and mutation databases Cosmic; 687565
Cosmic; 849857
Cosmic; 897441
Cosmic; 906823
Cosmic; 920820
Cosmic; 1175808
Cosmic; 1610750
Cosmic; 1746959
Cosmic; 2302324
Cosmic; 2367511
Proteomic databases PRIDE; PXD003914
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number22