ID   CCF-STTG1
AC   CVCL_1118
SY   CCFSTTG1; STTG1
DR   BTO; BTO:0003863
DR   CLO; CLO_0002329
DR   EFO; EFO_0002127
DR   CLDB; cl669
DR   CLDB; cl5177
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   ATCC; CRL-1718
DR   BioSample; SAMN01821545
DR   BioSample; SAMN03470976
DR   BioSample; SAMN10988114
DR   Cell_Model_Passport; SIDM00131
DR   ChEMBL-Cells; CHEMBL3308795
DR   ChEMBL-Targets; CHEMBL1075419
DR   CLS; 300388
DR   Cosmic; 687565
DR   Cosmic; 849857
DR   Cosmic; 897441
DR   Cosmic; 906823
DR   Cosmic; 920820
DR   Cosmic; 1175808
DR   Cosmic; 1610750
DR   Cosmic; 1746959
DR   Cosmic; 2302324
DR   Cosmic; 2367511
DR   Cosmic-CLP; 906823
DR   DepMap; ACH-000329
DR   ECACC; 90021502
DR   EGA; EGAS00001000978
DR   GDSC; 906823
DR   GEO; GSM326233
DR   GEO; GSM886923
DR   GEO; GSM887989
DR   GEO; GSM1374443
DR   GEO; GSM1669668
DR   IARC_TP53; 21217
DR   IGRhCellID; CCFSTTG1
DR   IZSLER; BS TCL 125
DR   LiGeA; CCLE_127
DR   LINCS_LDP; LCL-1394
DR   PharmacoDB; CCFSTTG1_188_2019
DR   PRIDE; PXD003914
DR   Progenetix; CVCL_1118
DR   RCB; RCB1977
DR   TKG; TKG 0581
DR   Wikidata; Q54808966
RX   DOI=10.1007/0-306-46861-1_11;
RX   PubMed=1404494;
RX   PubMed=3877740;
RX   PubMed=19435942;
RX   PubMed=20164919;
RX   PubMed=20215515;
RX   PubMed=22460905;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: PTEN genetic alteration cell panel (ATCC TCP-1030).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Mutation; HGNC; 5382; IDH1; None_reported; -; Zygosity=- (PubMed=19435942).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0.55%; Native American=0%; East Asian, North=1.13%; East Asian, South=0%; South Asian=0.6%; European, North=60.84%; European, South=36.87% (PubMed=30894373).
CC   Discontinued: RCB; RCB1977; true.
CC   Discontinued: TKG; TKG 0581; true.
ST   Source(s): ATCC; CLS; Cosmic-CLP; PubMed=25877200; RCB
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11,13
ST   D16S539: 11,12
ST   D18S51: 15
ST   D19S433: 15.2,16
ST   D21S11: 28,29
ST   D2S1338: 20,26
ST   D3S1358: 16,17
ST   D5S818: 12,13
ST   D7S820: 10,11
ST   D8S1179: 13,14
ST   FGA: 20,22
ST   Penta D: 11,13
ST   Penta E: 10
ST   TH01: 7,8
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   68Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 23-06-22; Version: 31
//
RX   DOI=10.1007/0-306-46861-1_11;
RA   Ali-Osman F.;
RT   "Brain tumors.";
RL   (In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York (1999).
//
RX   PubMed=1404494; DOI=10.1002/jnr.490320212;
RA   Krul E.S., Tang J.;
RT   "Secretion of apolipoprotein E by an astrocytoma cell line.";
RL   J. Neurosci. Res. 32:227-238(1992).
//
RX   PubMed=3877740; DOI=10.1016/0165-5728(85)90005-0;
RA   Barna B.P., Chou S.M., Jacobs B., Ransohoff R.M., Hahn J.F., Bay J.W.;
RT   "Enhanced DNA synthesis of human glial cells exposed to human
RT   leukocyte products.";
RL   J. Neuroimmunol. 10:151-158(1985).
//
RX   PubMed=19435942; DOI=10.1215/15228517-2009-025;
RA   Ichimura K., Pearson D.M., Kocialkowski S., Backlund L.M., Chan R.,
RA   Jones D.T.W., Collins V.P.;
RT   "IDH1 mutations are present in the majority of common adult gliomas
RT   but rare in primary glioblastomas.";
RL   Neuro-oncol. 11:341-347(2009).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S.,
RA   Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P.,
RA   Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H.,
RA   Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//