Cellosaurus CHP-126 (CVCL_1123)

Cell line name CHP-126
Synonyms CHP 126; CHP126
Accession CVCL_1123
Resource Identification Initiative To cite this cell line use: CHP-126 (RRID:CVCL_1123)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 44.5 hours (PubMed=10079).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Neuroblastoma (NCIt: C3270)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9506 ! CHP-126B1
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=11416159; PubMed=25877200; RCB

Markers:
AmelogeninX
CSF1PO12,13
D13S3178,9
D16S53912,13
D18S5113,16.1
D19S43313.2,14
D21S1130
D2S133817,24
D3S135816,18
D5S81812
D7S82011,14
D8S117912,15
FGA19,20
Penta D10,12
Penta E12,15
TH019
TPOX8
vWA15,16
Publications

PubMed=10079
Schlesinger H.R., Gerson J.M., Moorhead P.S., Maguire H., Hummeler K.
Establishment and characterization of human neuroblastoma cell lines.
Cancer Res. 36:3094-3100(1976)

PubMed=7139592; DOI=10.1016/0165-4608(82)90105-4
Gilbert F., Balaban G., Moorhead P.S., Bianchi D., Schlesinger H.R.
Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines.
Cancer Genet. Cytogenet. 7:33-42(1982)

PubMed=6888561; DOI=10.1038/305245a0
Schwab M., Alitalo K., Klempnauer K.-H., Varmus H.E., Bishop J.M., Gilbert F., Brodeur G.M., Goldstein M.N., Trent J.
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.
Nature 305:245-248(1983)

DOI=10.1016/B978-0-12-333530-2.50006-X
Israel M.A., Thiele C.J.
Tumor cell lines of the peripheral nervous system.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.43-78; Academic Press; New York (1994)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999)

PubMed=16822308; DOI=10.1186/1471-2407-6-177
Dam V., Morgan B.T., Mazanek P., Hogarty M.D.
Mutations in PIK3CA are infrequent in neuroblastoma.
BMC Cancer 6:177-177(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections CLS; 300432/NA
DSMZ; ACC-304
RCB; RCB0486
Cell line databases/resources CLDB; cl776
CCLE; CHP126_AUTONOMIC_GANGLIA
Cosmic-CLP; 910567
GDSC; 910567
LINCS_LDP; LCL-1973
Ontologies BTO; BTO:0005254
CLO; CLO_0002472
CLO; CLO_0050266
Biological sample resources BioSample; SAMN01821621
BioSample; SAMN03473117
Chemistry resources ChEMBL-Cells; CHEMBL3308252
ChEMBL-Targets; CHEMBL2366137
Gene expression databases GEO; GSM563360
GEO; GSM886929
GEO; GSM887995
GEO; GSM1366403
GEO; GSM1669676
Polymorphism and mutation databases Cosmic; 688062
Cosmic; 910567
Cosmic; 1019935
Cosmic; 2485942