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Cellosaurus CP66-MEL (CVCL_1144)

[Text version]

Cell line name CP66-MEL
Synonyms CP66MEL; CP66
Accession CVCL_1144
Resource Identification Initiative To cite this cell line use: CP66-MEL (RRID:CVCL_1144)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.27
East Asian, North0.56
East Asian, South0
South Asian2.13
European, North67.46
European, South29.58
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VU67 ! CP66-EBV
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81812,13
D7S82010,11
D13S31713
D16S53911
TH017,8
TPOX11,12
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; CP66MEL_SKIN
Cell_Model_Passport; SIDM00190
Cosmic-CLP; 753546
DepMap; ACH-002097
GDSC; 753546
LINCS_LDP; LCL-1271
Chemistry resources ChEMBL-Cells; CHEMBL3308287
ChEMBL-Targets; CHEMBL2366363
PharmacoDB; CP66MEL_261_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669706
Other Wikidata; Q54814370
Polymorphism and mutation databases Cosmic; 753546
Cosmic; 2230116
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number23