Cellosaurus CRO-AP2 (CVCL_1147)

Cell line name CRO-AP2
Synonyms CRO-AP/2; CROAP2; AP2
Accession CVCL_1147
Resource Identification Initiative To cite this cell line use: CRO-AP2 (RRID:CVCL_1147)
Comments Doubling time: ~20-40 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Derived from sampling site: Pleural effusion.
Disease Primary effusion lymphoma (NCIt: C6915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO11,12
D13S31711
D16S53911
D5S81812
D7S82010,11
TH016,8
TPOX10,11
vWA17,18
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=CRO-AP%2f2
Publications

PubMed=9389573; DOI=10.1002/(SICI)1097-0215(19971114)73:4<562::AID-IJC18>3.0.CO;2-B
Carbone A., Cilia A.M., Gloghini A., Canzonieri V., Pastore C., Todesco M., Cozzi M., Perin T., Volpe R., Pinto A., Gaidano G.
Establishment of HHV-8-positive and HHV-8-negative lymphoma cell lines from primary lymphomatous effusions.
Int. J. Cancer 73:562-569(1997)

PubMed=10784388; DOI=10.3109/10428190009148391
Carbone A., Cilia A.M., Gloghini A., Capello D., Perin T., Bontempo D., Canzonieri V., Tirelli U., Volpe R., Gaidano G.
Primary effusion lymphoma cell lines harbouring human herpesvirus type-8.
Leuk. Lymphoma 36:447-456(2000)

PubMed=20454443; DOI=10.1155/2010/904767
Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.
Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human and other primate cell lines.
J. Biomed. Biotechnol. 2010:904767-904767(2010)

PubMed=21685375; DOI=10.1182/blood-2010-12-323659
Roy D., Sin S.-H., Damania B., Dittmer D.P.
Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.
Blood 118:E32-E39(2011)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-48
Cell line databases/resources CLDB; cl3486
Cosmic-CLP; 906807
GDSC; 906807
IGRhCellID; CROAP2
Ontologies BTO; BTO:0002724
CLO; CLO_0002617
EFO; EFO_0002145
Biological sample resources BioSample; SAMN03473560
Chemistry resources ChEMBL-Cells; CHEMBL3308254
ChEMBL-Targets; CHEMBL2366080
Gene expression databases GEO; GSM634729
GEO; GSM1669709
Polymorphism and mutation databases Cosmic; 906807