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Cellosaurus CTB-1 (CVCL_1149)

[Text version]

Cell line name CTB-1
Synonyms CTB1
Accession CVCL_1149
Resource Identification Initiative To cite this cell line use: CTB-1 (RRID:CVCL_1149)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 36 hours (PubMed=21533490).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.23
East Asian, North25.3
East Asian, South74.47
South Asian0
European, North0
European, South0
Disease Diffuse large B-cell lymphoma (NCIt: C8851)
Derived from metastatic site: Pericardial effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX
CSF1PO12
D5S81811,13
D7S82011
D13S3178,9
D16S53911,12
TH019
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=21533490; DOI=10.3892/ijo.10.6.1103
Uchida Y., Miyazawa K., Yaguchi M., Gotoh A., Iwase O., Ohyashiki K., Toyama K.
Establishment of a novel B-lymphoma cell line, CTB-1, with strong Pas antigen expression having chromosomal translocation (14;22).
Int. J. Oncol. 10:1103-1107(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-J., Wheat L.M., Karran E.L., Garcia J.F., Sanchez L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414
Drexler H.G., Eberth S., Nagel S., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.
Leuk. Lymphoma 57:1015-1020(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections RCB; RCB1316
Cell line databases/resources CCLE; CTB1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00283
Cosmic-CLP; 949088
DepMap; ACH-002221
GDSC; 949088
LINCS_LDP; LCL-1118
Ontologies CLO; CLO_0050077
Biological sample resources BioSample; SAMN03472128
Chemistry resources ChEMBL-Cells; CHEMBL3308188
ChEMBL-Targets; CHEMBL2366344
PharmacoDB; CTB1_267_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM119489
GEO; GSM1669711
Other Wikidata; Q54814731
Polymorphism and mutation databases Cosmic; 949088
Cosmic; 2297019
Cosmic; 2437311
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number25