Cellosaurus D-263MG (CVCL_1154)

Cell line name D-263MG
Synonyms D-263 MG; D263MG
Accession CVCL_1154
Resource Identification Initiative To cite this cell line use: D-263MG (RRID:CVCL_1154)
Comments Problematic cell line: Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,12
D13S31714
D16S53911,12
D5S81811
D7S82010
TH018,9.3
TPOX8,11
vWA14,17
Publications

PubMed=2881426; DOI=10.1007/BF00687952
Bigner S.H., Friedman H.S., Biegel J.A., Wikstrand C.J., Mark J., Gebhardt R., Eng L.F., Bigner D.D.
Specific chromosomal abnormalities characterize four established cell lines derived from malignant human gliomas.
Acta Neuropathol. 72:86-97(1986)

PubMed=3011240; DOI=10.1016/0165-4608(86)90172-X
Bigner S.H., Mark J., Bullard D.E., Mahaley M.S. Jr., Bigner D.D.
Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations.
Cancer Genet. Cytogenet. 22:121-135(1986)

DOI=10.1016/B978-0-12-333530-2.50005-8
Nister M., Westermark B.
Human glioma cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York (1994)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line databases/resources Cosmic-CLP; 946368
GDSC; 946368
LINCS_LDP; LCL-1371
Chemistry resources ChEMBL-Cells; CHEMBL3308255
ChEMBL-Targets; CHEMBL2366183
Gene expression databases GEO; GSM1669716
Polymorphism and mutation databases Cosmic; 946368
Cosmic; 2367514