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Cellosaurus D-336MG (CVCL_1156)

[Text version]

Cell line name D-336MG
Synonyms D-336 MG; D336MG
Accession CVCL_1156
Resource Identification Initiative To cite this cell line use: D-336MG (RRID:CVCL_1156)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for TP53 p.Arg248Trp (c.742C>T) (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.62
Native American0.37
East Asian, North0.73
East Asian, South0
South Asian1.2
European, North68.29
European, South28.79
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10
D5S81810,13
D7S82010,11
D13S31712
D16S53911,12
TH016,9.3
TPOX8,9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=2253244
Bigner S.H., Humphrey P.A., Wong A.J., Vogelstein B., Mark J., Friedman H.S., Bigner D.D.
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.
Cancer Res. 50:8017-8022(1990)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; D336MG_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00620
Cosmic-CLP; 946369
DepMap; ACH-002226
GDSC; 946369
LINCS_LDP; LCL-1372
Chemistry resources ChEMBL-Cells; CHEMBL3308844
ChEMBL-Targets; CHEMBL2366113
PharmacoDB; D336MG_274_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669718
Other Wikidata; Q54817130
Polymorphism and mutation databases Cosmic; 946369
Cosmic; 2367515
IARC_TP53; 27149
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22