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Cellosaurus D-423MG (CVCL_1160)

[Text version]

Cell line name D-423MG
Synonyms D-423 MG; D423MG
Accession CVCL_1160
Resource Identification Initiative To cite this cell line use: D-423MG (RRID:CVCL_1160)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.32
East Asian, North1.3
East Asian, South1.42
South Asian0.18
European, North68.67
European, South28.1
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO10
D5S81811,13
D7S82011
D13S31711,12
D16S5399,11
TH016,9
TPOX8
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; D423MG_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00209
Cosmic-CLP; 946372
DepMap; ACH-002228
GDSC; 946372
LINCS_LDP; LCL-1374
Chemistry resources ChEMBL-Cells; CHEMBL3308257
ChEMBL-Targets; CHEMBL2366134
PharmacoDB; D423MG_276_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669720
Other Wikidata; Q54817135
Polymorphism and mutation databases Cosmic; 946372
Cosmic; 2367518
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number23