Cell line name | D-423MG | ||||||||||||||||||
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Synonyms | D-423 MG; D423MG | ||||||||||||||||||
Accession | CVCL_1160 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: D-423MG (RRID:CVCL_1160) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||
Sequence variations | Homozygous for PTEN p.Arg173Cys (c.517C>T) (ClinVar=VCV000189500) (CCLE; Cosmic-CLP).Homozygous for TP53 p.Gly245Ser (c.733G>A) (ClinVar=VCV000012365) (CCLE; Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=20164919; DOI=10.1038/nature08768 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line databases/resources | CCLE; D423MG_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00209 Cosmic-CLP; 946372 DepMap; ACH-002228 LINCS_LDP; LCL-1374 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308257
ChEMBL-Targets; CHEMBL2366134 GDSC; 946372 PharmacoDB; D423MG_276_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM1669720 | ||||||||||||||||||
Other | Wikidata; Q54817135 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 946372
Cosmic; 2367518 IARC_TP53; 27151 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||
Version number | 26 |