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Cellosaurus D-542MG (CVCL_1164)

[Text version]

Cell line name D-542MG
Synonyms D542MG
Accession CVCL_1164
Resource Identification Initiative To cite this cell line use: D-542MG (RRID:CVCL_1164)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.45
Native American2.46
East Asian, North53.35
East Asian, South39.58
South Asian0
European, North1
European, South3.16
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VU88 ! L542
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO11,13
D5S81810,12
D7S8209,11
D13S31710
D16S53910,13
TH016,9
TPOX11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; D542MG_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00207
Cosmic-CLP; 753549
DepMap; ACH-002230
GDSC; 753549
LINCS_LDP; LCL-1376
Chemistry resources ChEMBL-Cells; CHEMBL3308259
ChEMBL-Targets; CHEMBL2366208
PharmacoDB; D542MG_278_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669722
Other Wikidata; Q54817139
Polymorphism and mutation databases Cosmic; 753549
Cosmic; 2367521
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number21