Cell line name | EC-GI-10 | ||||||||||||||||||||||||||
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Synonyms | ECGI10; EC-GI | ||||||||||||||||||||||||||
Accession | CVCL_1187 | ||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: EC-GI-10 (RRID:CVCL_1187) | ||||||||||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Population: Japanese. Characteristics: Established from a mouse xenograft. Doubling time: ~31 hours (PubMed=2824416). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||||||||||
Sequence variations | Heterozygous for TP53 p.Tyr234Cys (c.701A>G) (ClinVar=VCV000127820) and p.Arg273Leu (c.818G>T) (ClinVar=VCV000376655) (CCLE; Cosmic-CLP). | ||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Esophageal squamous cell carcinoma (NCIt: C4024) Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977) Derived from metastatic site: Lymph node. | ||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||||||||||
Age at sampling | 65Y | ||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; PubMed=11416159; RCB Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||
Publications | PubMed=2824416; DOI=10.20772/cancersci1985.78.10_1044 PubMed=3261732; DOI=10.1210/jcem-67-3-592 PubMed=20164919; DOI=10.1038/nature08768 PubMed=22460905; DOI=10.1038/nature11003 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||
Cell line collections | RCB; RCB0774 | ||||||||||||||||||||||||||
Cell line databases/resources | CCLE; ECGI10_OESOPHAGUS
Cell_Model_Passport; SIDM00278 Cosmic-CLP; 753555 DepMap; ACH-000305 LINCS_LDP; LCL-1151 | ||||||||||||||||||||||||||
Ontologies | CLO; CLO_0051378 | ||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03472227
BioSample; SAMN10987728 | ||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308289
ChEMBL-Targets; CHEMBL2366240 GDSC; 753555 PharmacoDB; ECGI10_316_2019 | ||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM886996 GEO; GSM888065 GEO; GSM1669753 | ||||||||||||||||||||||||||
Other | Wikidata; Q54831834 | ||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 753555
IARC_TP53; 21317 LiGeA; CCLE_378 Progenetix; CVCL_1187 | ||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||||||||||
Version number | 28 |