Cellosaurus EC-GI-10 (CVCL_1187)

Cell line name EC-GI-10
Synonyms ECGI10; EC-GI
Accession CVCL_1187
Resource Identification Initiative To cite this cell line use: EC-GI-10 (RRID:CVCL_1187)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~31 hours (PubMed=2824416).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; PubMed=11416159; RCB

Markers:
AmelogeninX,Y
CSF1PO10,11
D13S31711
D16S53911,12
D18S5119
D21S1131
D5S81811
D7S8208,11
D8S11799,13
FGA21,24
TH017,9
TPOX11
vWA16,18
Publications

PubMed=2824416; DOI=10.20772/cancersci1985.78.10_1044
Sato K., Kasono K., Ohba Y., Yashiro T., Fujii Y., Yoshida M.A., Tsushima T., Shizume K.
Establishment of a parathyroid hormone-like factor-producing esophageal carcinoma cell line (EC-GI).
Jpn. J. Cancer Res. 78:1044-1048(1987)

PubMed=3261732; DOI=10.1210/jcem-67-3-592
Sato K., Fujii Y., Kasono K., Tsushima T., Shizume K.
Production of interleukin-1 alpha and a parathyroid hormone-like factor by a squamous cell carcinoma of the esophagus (EC-GI) derived from a patient with hypercalcemia.
J. Clin. Endocrinol. Metab. 67:592-601(1988)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections RCB; RCB0774
Cell line databases/resources CCLE; ECGI10_OESOPHAGUS
Cosmic-CLP; 753555
GDSC; 753555
LINCS_LDP; LCL-1151
Ontologies CLO; CLO_0051378
Biological sample resources BioSample; SAMN03472227
Chemistry resources ChEMBL-Cells; CHEMBL3308289
ChEMBL-Targets; CHEMBL2366240
Gene expression databases GEO; GSM886996
GEO; GSM888065
GEO; GSM1669753
Polymorphism and mutation databases Cosmic; 753555