Cellosaurus ECC12 (CVCL_1189)

Cell line name ECC12
Synonyms ECC-12
Accession CVCL_1189
Resource Identification Initiative To cite this cell line use: ECC12 (RRID:CVCL_1189)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Gastric small cell neuroendocrine carcinoma (NCIt: C6764)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX,Y
CSF1PO11
D13S31712
D16S5399,11
D5S81813
D7S82010,11
TH019
TPOX11
vWA16,19
Publications

PubMed=8392984; DOI=10.1002/ijc.2910540617
Fujiwara T., Motoyama T., Ishihara N., Watanabe H., Kumanishi T., Kato K., Ichinose H., Nagatsu T.
Characterization of four new cell lines derived from small-cell gastrointestinal carcinoma.
Int. J. Cancer 54:965-971(1993)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections RCB; RCB1009
Cell line databases/resources CCLE; ECC12_STOMACH
Cosmic-CLP; 906849
GDSC; 906849
LINCS_LDP; LCL-1898
Ontologies CLO; CLO_0050807
Biological sample resources BioSample; SAMN03472198
Chemistry resources ChEMBL-Cells; CHEMBL3308192
ChEMBL-Targets; CHEMBL2366180
Gene expression databases GEO; GSM886995
GEO; GSM888064
GEO; GSM1669751
Polymorphism and mutation databases Cosmic; 848377
Cosmic; 906849
Cosmic; 1187270