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Cellosaurus ES5 (CVCL_1201)

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Cell line name ES5
Accession CVCL_1201
Resource Identification Initiative To cite this cell line use: ES5 (RRID:CVCL_1201)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for TP53 p.Arg248Gln (c.743G>A) (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.1
Native American0
East Asian, North1.85
East Asian, South0
South Asian0.47
European, North64.55
European, South32.03
Disease Ewing sarcoma (NCIt: C4817)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11,13
D5S81813
D7S8209,11
D13S31712,14
D16S53911,12
TH017
TPOX8
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; ES5_BONE
Cell_Model_Passport; SIDM00263
Cosmic-CLP; 684057
DepMap; ACH-002106
GDSC; 684057
LINCS_LDP; LCL-1442
Chemistry resources ChEMBL-Cells; CHEMBL3308517
ChEMBL-Targets; CHEMBL2366312
PharmacoDB; ES5_341_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669772
Other Wikidata; Q54832638
Polymorphism and mutation databases Cosmic; 684057
IARC_TP53; 27156
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22